Figure 3.

Lymphocyte cell counts and serum immunoglobulins in patients with vasculitis due to RAG deficiency. (A) CD3⁺ T cells, CD4⁺ T cells, naïve CD4⁺CD45RA⁺ T cells, CD8⁺ T cells, CD56⁺ NK cells, and CD19⁺ B cells of age-matched healthy controls (n = 25), RAG deficient patients with (n = 8) without (n = 46) vasculitis (B) Immunoglobulin titers of age-matched healthy controls (n = 25) RAG deficient patients with (n = 8) without (n = 46) vasculitis. Dashed line represents normal values. Statistically significant differences obtained in intergroup comparisons were confirmed by Mann Whitney U-test. Values of p < 0.05 were considered as significant (ns statistically not significant, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001).