Table 3.
Investigation of the Effect of the ACSL5 and GPX3 SNPs on Fat-Free Mass in the MEND-MND Cohorts
| Model | Sample Group | SNP/Allele | Effect (kg) | SE (kg) | p Value |
|---|---|---|---|---|---|
| Linear regression analysis at first visit | cases | rs58854276/A | −2.0 | 1.3 | 0.14 |
| Linear regression analysis at first visit | cases | rs3828599/A | −1.0 | 1.3 | 0.47 |
| Linear regression analysis at first visit | controls | rs58854276/A | −0.1 | 1.0 | 0.89 |
| Linear regression analysis at first visit | controls | rs3828599/A | 0.2 | 1.2 | 0.89 |
| Repeated-measures linear mixed model | cases | rs58854276/A | −2.1 | 1.3 | 0.053 |
| Repeated-measures linear mixed model | cases | rs3828599/A | −1.0 | 1.3 | 0.22 |
First visit refers to the time of blood sampling for controls. In all analyses, sex was used as a covariate.