Table 1. Patient response to the oral fish collagen challenge test.
Time after OFC (min) | Dose of fish collagen* (g) | Vital sign | Symptoms and signs | Treatment | |
---|---|---|---|---|---|
SpO2 (%) | BP (mmHg) | ||||
Before OFC | 98 | 97/61 | No symptoms | ||
0 | 0.3 | ||||
1 | 100 | 103/57 | Discomfort in the pharynx and larynx | Oral antihistamines | |
15 | 100 | 97/64 | Pharyngeal obstruction and moderate abdominal pain | Nebulized adrenaline | |
50 | 100 | 106/84 | Cold distal limbs | Infusion of normal saline and prednisolone | |
115 | 100 | 103/57 | Redness and a wheal around the face | ||
180 | 98 | 94/51 | All symptoms and signs resolved |
OFC, oral food challenge test; SpO2, percutaneous oxygen saturation; BP, blood pressure.
*A sample of the fish collagen used in the gummy tablets was provided by the manufacturer; 1 g was added to 3 mL of water and melted in a 500-W microwave for 30 seconds. The patient consumed 1 g of the product, equivalent to 0.3 g of fish collagen.