Table 3.
ROC analysis results for independent variables for differentiation of asymptomatic patients with and without CT findings and between patients who developed symptoms later and those who remained asymptomatic.
| Variable | AUC (upper and lower limit) | SE AUC | Se | Sp | Optimal cut point |
|---|---|---|---|---|---|
| Patients with and without CT infiltrates | |||||
| Contact with SARS-CoV-2 positive patient (positive) | 0.67 (0.56–0.79) | 0.058 | 0.73 | 0.62 | N/A binary |
| Body temperature | 0.75 (0.64–0.86) | 0.058 | 0.75 | 0.77 | 36.7 °C |
| Diastolic blood pressure | 0.61 (0.48–0.74) | 0.066 | 0.46 | 0.73 | 92 mmHg |
| CRP | 0.77 (0.65–0.88) | 0.060 | 0.64 | 0.80 | 2.85 mg/L |
| KL-6 | 0.75 (0.58–0.91) | 0.085 | 0.73 | 0.67 | 216 U/mL |
| WBC | 0.63 (0.54–0.80) | 0.066 | 0.64 | 0.67 | 5.63 × 109/L |
| PT (INR) | 0.66 (0.51–0.80) | 0.075 | 0.60 | 0.71 | 0.99 |
| Patients who went on to develop symptoms vs. those who remained asymptomatic | |||||
| Infiltrate volume | 0.71 (0.56–0.86) | 0.078 | 0.75 | 0.71 | 59.1 cm3 |
| Percent lung involvement | 0.71 (0.56–0.86) | 0.077 | 0.63 | 0.79 | 1.96% |
| Whole lung attenuation | 0.68 (0.53–0.83) | 0.078 | 0.63 | 0.63 | - 840 HU |
| Consolidation (present) | 0.67 (0.53–0.80) | 0.069 | 0.71 | 0.63 | N/A binary |
Abbreviations: AUC, area under curve; SE, standard error; Se, sensitivity; Sp, specificity; CT, computed tomography; CRP, C-reactive protein; PT (INR), prothrombin time calculated as international normalized ratio; WBC, white blood cell count; HU, Hounsfield unit