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. 2020 Nov 3;3(11):e2023774. doi: 10.1001/jamanetworkopen.2020.23774

Table 3. Model Output for Brain Regions of Interest.

Brain ROIs Neighborhood poverty Household income PRFQ
β (95% CIs) t P value β (95% CIs) t P value β (95% CIs) t P value
Model 1a
Right hippocampus NA NA NA 0.06 (0.05 to 0.08) 7.16 <.001 –0.02 (–0.04 to –0.01) –2.63 .01
Left hippocampus NA NA NA 0.07 (0.05 to 0.09) 7.73 <.001 –0.01 (–0.03 to 0.01) –1.32 .19
Right SFG NA NA NA 0.10 (0.08 to 0.12) 11.35 <.001 –0.02 (–0.03 to 0) –1.78 .09
Left SFG NA NA NA 0.09 (0.07 to 0.10) 10.22 <.001 –0.01 (–0.03 to 0) –1.73 .09
Right DLPFC NA NA NA 0.12 (0.10 to 0.13) 14.58 <.001 –0.02 (–0.03 to 0) –2.35 .03
Left DLPFC NA NA NA 0.11 (0.10 to 0.13) 14.39 <.001 –0.01 (–0.03 to 0) –1.93 .07
Right DMPFC NA NA NA 0.10 (0.08 to 0.12) 12.56 <.001 –0.02 (–0.04 to –0.01) –2.68 .01
Left DMPFC NA NA NA 0.10 (0.08 to 0.11) 12.25 <.001 –0.02 (–0.03 to 0) –2.5 .01
Model 2b
Right hippocampus –0.08 (–0.10 to –0.06) –8.35 <.001 NA NA NA NA NA NA
Left hippocampus –0.06 (–0.08 to –0.05) –6.77 .04 NA NA NA NA NA NA
Right SFG –0.11 (–0.12 to –0.09) –11.5 <.001 NA NA NA NA NA NA
Left SFG –0.10 (–0.12 to –0.08) –10.97 <.001 NA NA NA NA NA NA
Right DLPFC –0.15 (–0.17 to –0.13) –17.5 <.001 NA NA NA NA NA NA
Left DLPFC –0.13 (–0.15 to –0.12) –16.75 <.001 NA NA NA NA NA NA
Right DMPFC –0.12 (–0.13 to –0.1) –14.21 <.001 NA NA NA NA NA NA
Left DMPFC –0.11 (–0.12 to –0.09) –13.98 <.001 NA NA NA NA NA NA
Model 3c
Right hippocampus –0.04 (–0.06 to –0.01) –2.89 .01 0.04 (0.02 to 0.07) 4.14 <.001 –0.02 (–0.04 to –0.01) –2.6 .05
Left hippocampus –0.02 (–0.04 to –0.01) –1.29 .21 0.06 (0.04 to 0.08) 5.55 <.001 NA NA NA
Right SFG –0.05 (–0.08 to –0.03) –4.24 <.001 0.08 (0.06 to 0.1) 7.4 <.001 NA NA NA
Left SFG –0.05 (–0.07 to –0.03) –4.29 <.001 0.07 (0.05 to 0.09) 6.43 <.001 NA NA NA
Right DLPFC –0.09 (–0.12 to –0.07) –8.43 <.001 0.08 (0.06 to 0.1) 7.83 <.001 –0.01 (–0.03 to 0) –1.68 .09
Left DLPFC –0.08 (–0.1 to –0.06) –7.7 <.001 0.07 (0.06 to 0.09) 8.06 <.001 NA NA NA
Right DMPFC –0.07 (–0.09 to –0.05) –6.08 <.001 0.07 (0.05 to 0.09) 7.54 <.001 –0.01 (–0.03 to 0) –1.72 .12
Left DMPFC –0.06 (–0.08 to –0.04) –5.88 <.001 0.07 (0.05 to 0.08) 7.25 <.001 –0.01 (–0.03 to 0) –1.69 .12

Abbreviations: DLPFC, dorsal lateral prefrontal cortex; DMPFC, dorsal medial prefrontal cortex; NA, not applicable; PRFQ, Parent-Reported Financial Adversity Questionnaire; ROI, region of interest; SFG, superior frontal gyrus.

a

Model 1 included household income and PRFQ as factors with age, sex, and intracranial volume included as covariates.

b

Model 2 included neighborhood poverty as a factor, with age, sex, and intracranial volume included as covariates.

c

Model 3 included household income, PRFQ, and neighborhood poverty as factors with age, sex, and intracranial volume included as covariates.