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. 2020 Nov 3;3(11):e2023774. doi: 10.1001/jamanetworkopen.2020.23774

Table 4. Model Output for SEM Analyses Investigating Plausibility of Mediationa.

Factor Path a, NP and brain factors Path b, brain factors and cognitive tasks Path a × b, indirect effect Path c, NP and cognitive tasks with brain factors in model
Estimate (SE) z P value Estimate (SE) z P value Estimate (SE) z P value Estimate (SE) z P value
Picture vocabulary
NP NA NA NA NA NA NA NA NA NA –0.15 (0.02) –10.26 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.15 (0.02) 7.41 <.001 –0.03 (0.01) –7.02 <.001 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.07 (0.02) 3.87 <.001 –0.01 (0.004) –3.77 <.001 NA NA NA
Oral reading
NP NA NA NA NA NA NA NA NA NA –0.06 (0.02) –3.61 <.001
Prefrontal Factor –0.23 (0.01) –21.27 <.001 0.08 (0.02) 3.82 <.001 –0.02 (0.01) –3.75 <.001 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.07 (0.02) 3.68 <.001 –0.01 (0.004) –3.52 <.001 NA NA NA
Dimensional card sort
NP NA NA NA NA NA NA NA NA –0.1 (0.02) –6.75 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.07 (0.02) 3.33 <.01 –0.02 (0.01) –3.27 .001 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.04 (0.02) 1.9 .06 –0.01 (0.004) –1.89 .06 NA NA NA
Flanker inhibitory control
NP NA NA NA NA NA NA NA NA NA –0.08 (0.02) –4.63 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.06 (0.02) 2.64 .01 –0.01 (0.01) –2.62 .01 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.04 (0.02) 1.85 .06 –0.01 (0.004) –1.84 .07 NA NA NA
List sorting
NP NA NA NA NA NA NA NA NA NA –0.12 (0.02) –7.63 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.12 (0.02) 5.73 <.001 –0.03 (0.01) –5.56 <.001 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.02 (0.02) 0.92 .36 –0.01 (0.004) –0.92 .36 NA NA NA
Pattern comparison
NP NA NA NA NA NA NA NA NA NA –0.07 (0.02) –4.5 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.04 (0.02) 1.83 .07 –0.01 (0.01) –1.82 .07 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.02 (0.02) 1.16 .25 –0.01 (0.004) –1.15 .25 NA NA NA
Picture sequence
NP NA NA NA NA NA NA NA NA NA –0.07 (0.02) –4.32 <.001
Prefrontal factor –0.23 (0.01) –21.27 <.001 0.06 (0.02) 2.97 .008 –0.02 (0.01) –2.93 <.001 NA NA NA
Hippocampal factor –0.19 (0.01) –16.15 <.001 0.07 (0.02) 3.49 <.001 –0.01 (0.004) –3.42 <.001 NA NA NA

Abbreviations: NA, not applicable; NP, neighborhood poverty.

a

Covariates included: age, sex, household income, and intracranial volume. Fit indices suggest that models were a good fit for the data: Prefrontal models (CFI = 0.936, RMSEA = 0.087, SRMR = 0.071); Hippocampal models (CFI = 0.940, RMSEA = 0.084, SRMR = 0.053). NP was modeled as the predictor with prefrontal and hippocampal factors as mediators, with separate cognitive tasks as the outcome (7 models total).