Table 1.
Formulations | Particle size (nm) | Polydispersity index | Zeta potential (mV) | Entrapment efficiency of Dox (%) |
---|---|---|---|---|
Dox-PEG-LPs | 134.1 ± 0.6 | 0.031 | 17.5 ± 2.9 | 95.9 ± 1.8 |
Dox-TPGS-LPs | 132.8 ± 1.1 | 0.053 | 32.7 ± 2.4 | 95.2 ± 2.1 |
Bcl-2 siRNA/Dox-PEG-LPs | 178.0 ± 2.3 | 0.109 | 7.2 ± 1.8 | 95.6 ± 2.3 |
Bcl-2 siRNA/Dox-TPGS-LPs | 192.4 ± 2.8 | 0.179 | 12.7 ± 2.1 | 95.1 ± 1.9 |