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The priming effect of FAM-siRNA corona on the improvement of Dox uptake in Bel7402/5-FU cells.
| MFI±SD | (1) PEG group | (2) TPGS group | MFI(2)/MFI(1) |
|---|---|---|---|
| (a) add siRNA# | 34.8 ± 0.3 | 51.3 ± 1.8 | 1.47⁎⁎ |
| (b) only Dox | 30.1 ± 0.6 | 40.4 ± 0.7 | 1.34⁎⁎ |
| MFI(a)/MFI(b) | 1.16* | 1.27⁎⁎ |
(1)(a) FAM-siRNA/Dox-PEG-LPs; (1)(b) Dox-PEG-LPs;.
(2)(a) FAM-siRNA/Dox-TPGS-LPs; (2)(b) Dox-TPGS-LPs.
MFI: mean fluorescence intensity of intracellular Dox.
*P < 0.05. **P < 0.05.
