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. 2019 Nov 12;15(5):646–660. doi: 10.1016/j.ajps.2019.10.003

Table 3.

IC50 values of four Dox formulations against Bel7402 and Bel7402/5-FU cells calculated from MTT assay.

Formulations IC50 values (µg/ml)
Bel7402
Bel7402/5FU
24 h 48 h 24 h 48 h
Free Dox 2.71 0.45 >100 12.03
Dox-PEG-LPs 1.51 0.20 55.09 1.97
Dox-TPGS-LPs 1.01 0.15 16.10 0.64
Bcl-2 siRNA/Dox-TPGS-LPs 0.40 0.09 4.31 0.18