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. Author manuscript; available in PMC: 2020 Nov 4.
Published in final edited form as: Nat Cell Biol. 2020 Mar 16;22(4):412–424. doi: 10.1038/s41556-020-0481-4

Extended Data 4. Genetic ablation of Ctr1 reduces KrasG12D-driven lung tumorigenesis.

Extended Data 4.

a, Normalized representative images of in vivo luminescence of KrasG12D/+;Trp53flox/flox;Rosa26::LSL-Luc (KPLuc) mice introduced with either sgRNA against β-GAL or Ctr1 at week 16 endpoint. b,c, Scatter dot plot with bar at mean ΔLuminescence units from week 10 to week 16 from KPLuc mice introduced with either sgRNA against β-GAL or Ctr1. n=6 biologically independent animals. Results were compared using an unpaired, one-tailed Student’s t-test. P=0.0818.