In vitro test of the LAD with heparinized bovine blood at various blood flow rates: a) oxygen saturation level before and after the LAD in oxygen, b) oxygen uptake in oxygen, c) normalized oxygen transfer of the LAD when it was tested in oxygen environment, d) oxygen saturation level before and after the LAD in room air, e) oxygen uptake in room air, f) normalized oxygen transfer of the LAD when it was tested in room air, g) pressure drops for the LAD (the shaded region indicates the operational pressure drops range for a pumpless operation), and h) the pressure drops for the LAD with the extracorporeal circuit. Data are means ± SD, n = 3. Hematocrit was 38% and 29% for oxygen and air conditions, respectively.