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Knockdown of MDM2 rescues P53 and P21 expression. MDM2, P53 and P21 expression was detected following MDM2 knockdown. **P<0.01 and ***P<0.001. lncRNA PCAT6, long non-coding RNA prostate cancer-associated transcript 6; NC, negative control; OE, overexpression; MDM2, E3 ubiquitin-protein ligase Mdm2; si, small interfering RNA.
