Extended Data Fig. 7. Micro-anatomical locations of splenic YFP⁺ cells during MCMV infection of Ifnb1^Eyfp mice.

(a, b, c) Number of IFN-α/β spots per mm² (a), of YFP⁺IFN-α/β⁺ cells/mm² (b), and of YFP⁺ cells per mm² (c), in whole spleen sections from Ifnb1^Eyfp mice at indicated time points after MCMV infection. (d) Number of YFP⁺ cells per mm² residing in the different spleen zones. MZ, marginal zone; RP, red pulp; WP, white pulp. Fifteen individual data points are shown on each graph for each time point, corresponding to quantitation of 5 different whole spleen sections per mouse, from 3 different mice, with overlay of mean±s.e.m.