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. Author manuscript; available in PMC: 2021 Mar 24.
Published in final edited form as: Mol Psychiatry. 2019 Aug 30;26(4):1310–1320. doi: 10.1038/s41380-019-0502-5

Figure 1.

Figure 1

Placebo and an active treatment are administered in a randomized controlled trial. Over the course of the trial the individuals receiving the active treatment show both a larger response, and more variability in their response. This implies that the active treatment is more effective in some individuals and less effective in others, whereas the placebo is associated with a more uniform response across individuals.