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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Feb 4;41(4):1446–1458. doi: 10.1161/ATVBAHA.120.315321

Figure 2. Partial least squares discriminate analysis able to differentiate SLE patients from HC.

Figure 2

Metabolomic data from 80 patients with SLE and 39 healthy controls (HC) were analysed using a NMR platform. (A) sPLS-DA performed on 50 metabolic markers following model optimisation separated SLE patients from healthy controls. (B) Features included in the sPLS-DA are plotted with their factor loading value. (C) Visualisation of the weighting and correlation of each metabolite in component 1 and 2 on the sPLS-DA model. Abbreviations: HDL, high density lipoprotein: LDL, low density lipoprotein: VLDL, very low density lipoprotein: IDL, intermediate density lipoprotein: XXL, chylomicrons and extremely large: XL, very large: L, large: M, medium: S, small: XS very small: PL, phospholipids: C, total cholesterol: CE, cholesterol esters: FC, free cholesterol: TG, triglycerides: P, particle: D, diameter: see Supplementary Table III for full list of metabolite abbreviations).