Table 3.

Cellular accumulation of Pt in A2780 cells and A549 cells after exposure to unfunctionalised 1, mono- and di-functionalised complexes 2a–2c and 3a–3c, respectively (2 μM, 1 h, in the dark)

Cell	Complex	Pta (ng per 106 cells)
A549	1	0.51 ± 0.03***
	2a	9.8 ± 2.1*
	3a	36.1 ± 1.5***
A2780	1	0.16 ± 0.02*
	2a	6.2 ± 0.5**
	2b	3.5 ± 0.4***
	2c	10.8 ± 0.3***
	3a	90.9 ± 12.0***
	3b	61.4 ± 5.0***
	3c	53.8 ± 1.9***

^aAll data were determined from triplicate samples and their statistical significance compared to untreated cells evaluated by a two-tail t-test with unequal variances. *p < 0.05, **p < 0.01, ***p < 0.005.