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. Author manuscript; available in PMC: 2021 Mar 29.
Published in final edited form as: Nature. 2019 Jan 2;565(7738):251–254. doi: 10.1038/s41586-018-0836-1

Extended Data Figure 4. Power analysis in different locations of kinetic parameter space.

Extended Data Figure 4

The power of detecting 4-fold changes in burst frequency and size as a function of the number of cells depending on the location of transcriptional burst kinetic parameters in parameter space (A-J). Upper panels: Analysis of power for burst frequency and size in indicated location in parameter space. Lower panels: Histogram with expression distributions over cells at the different locations in parameter space.