Extended Data Fig. 6. The effect on SiR-PyPDS binding on unfolding kinetics of G4 DNA sequences in vitro.
G4 two-phase unfolding kinetics were measured by introducing 10 μM of respective complimentary DNA oligonucleotide at t = 0 to trap the unfolded G4 oligonucleotide state. Data presented here are of best fit of a two-phase association model. Error indicates the standard error of the fit. n = 1 measurement for each condition. Each experiment has been repeated 3 times providing consistent results