Figure 2. Different conformations of the RagA2B2 transporter revealed by cryo-EM.
a-c, Cartoon views for closed-closed RagA2B2 (CC; a), open-closed (OC; b) and open-open (OO; c). Views are from the plane of the OM (left and middle panels) and from the extracellular space (right panel). Bound peptide is shown as space filling models in magenta. The plug domains o RagA are coloured dark blue.