Table 1. Measures of motor thresholds and cortical inhibition across the three groups.
Manic BD (n = 39) | Remitted FEM (n = 28) | HS (n = 45) | Fa | Pb | Post hoc LSD | |
---|---|---|---|---|---|---|
RMT | 39.36 (8.33) | 32.25 (6.08) | 36.69 (7.23) | 7.582 | <.001 | Manic BD=HS>remitted FEM |
SI1 mV | 53.59 (11.97) | 41.32 (8.04) | 48.40 (11.43) | 10.332 | <.001 | Manic BD>HS>remitted FEM |
SICI (%) | 15.68 (44.96) | 14.03 (46.51) | 35.88 (27.90) | 3.790 | .026 | HS>manic BD=remitted FEM |
LICI (%) | 75.01 (20.52) | 72.98 (24.72) | 57.81 (45.38) | 3.212 | .044 | HS<manic BD=remitted FEM |
All values are expressed as mean (standard deviation).
Degrees of freedom 2, 111.
Probability error for the one-way ANOVA omnibus test.
BD, bipolar disorder; FEM, first episode mania; HS, healthy subject; RMT, resting motor threshold (% of maximum machine output); MT1, motor threshold 1 (% of maximum machine output); SICI, % effective inhibition measured using short-interval intracortical inhibition; LICI, % effective inhibition measured using long-interval intracortical inhibition; LSD, least significant difference; SI1 mV, stimulation intensity to elicit a 1-mV motor evoked potential. The bold values indicate that the P values are statistically significant. (ie, P < 0.05).