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. Author manuscript; available in PMC: 2021 Apr 6.
Published in final edited form as: Chem Rev. 2014 Apr 10;114(11):5815–47. doi: 10.1021/cr400401e

Figure 10. 4Å resolution structure of torpedo acetylcholine receptor (left) and crystal structure of AChBP, which is homologues to the extracellular nAChR domain (right).

Figure 10

Left: 4Å resolution structure of torpedo acetylcholine receptor showing the extracellular, transmembrane and intracellular domains.3 The receptor is made of five subunits (each subunit is shown in a different color). Right: 2.2Å resolution crystal structure of AChBP, which is homologues to the extracellular (ligand binding) nAChR domain.4 This protein is a pentamer with five identical subunits surrounding the channel pore. The β-sheets are shown in green and α-helices in pink.