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. Author manuscript; available in PMC: 2021 Apr 6.
Published in final edited form as: Nat Immunol. 2021 Mar 11;22(4):510–519. doi: 10.1038/s41590-021-00894-5

Extended Data Fig. 5. Peyer’s Patch structure in Ltbr conditional knock out mice.

Extended Data Fig. 5

a, Microscopy images showing PP of adult mice conditionally ablated for Ltbr in indicated Cre mouse lines. b-c, Mean fluorescence intensity analysis of indicated markers enumerated from microscopy images of adult Ccl19 eYFP Ltbr +/+ and Ccl19 eYFP Ltbr fl/fl PPs (n=4 mice per group). d, Confocal microscope images showing sections of adult Ccl19 eYFP Col6a1 eYFP Ltbr fl/fl and Ccl19 eYFP Co/6α1 eYFP Ltbr +/+ PPs. e, Images show EYFP+RANKL+MADCAM1+ MRC networks in PPs of indicated adult mice. f, Images show EYFP+CD21/35+ FDC networks in PPs of indicated adult mice. Scale bars, 500 μm (a,d), 20 μm (e,f). Images are representative of 3-5 mice from 2 independent experiments. (b,c) Mean percentages and SD are indicated; P values as per two-sided Student’s t-test.