Figure 7.

Using therapy platforms to drive discovery, translation and application to unmet patient needs in a reinforcement loop. Starting from the bottom right, a patient requires a therapy and has access to it from the “existing” platform capability. However, the patient can also be enrolled in a study and the “scientific instruments” unlocked in a clinical trial. Researchers can then apply this toolkit to explore new therapies and mechanisms of action. The most promising concepts are applied in updates to the system, which then improve the baseline therapy for future patients.