Table 5. Characteristics of patient cohorts stratified by inpatient mortality.
Alive (n = 4,406) | Died as inpatient (n = 166) | p | |||
---|---|---|---|---|---|
mean ± SD/count | column, % | mean ± SD/count | column, % | ||
Pre-operative creatinine | 96.6 ± 37.5 | 120.5 ± 66.2 | <0.001 | ||
Age, years | 66.8 ± 11 | 70.4 ± 11 | <0.001 | ||
Sex | <0.05 | ||||
Female | 1,273 | 28.9 | 67 | 40.4 | |
Male | 3,133 | 71.1 | 99 | 59.6 | |
Dyspnoea status | <0.001 | ||||
NYHA I | 1,073 | 24.4 | 30 | 18.1 | |
NYHA II | 1,110 | 25.2 | 23 | 13.9 | |
NYHA III | 1,807 | 41 | 72 | 43.4 | |
NYHA IV | 416 | 9.4 | 41 | 24.7 | |
Previous MI | <0.05 | ||||
None | 2,954 | 67 | 99 | 56.9 | |
One | 1,141 | 25.9 | 47 | 28.3 | |
Two or more | 304 | 6.9 | 19 | 11.4 | |
Unknown | 7 | 0.2 | 1 | 0.6 | |
Active endocarditis | <0.001 | ||||
yes | 87 | 2 | 13 | 7.8 | |
Last MI | <0.001 | ||||
MI <6 h | 0 | 0 | 1 | 0.6 | |
MI >90 days | 724 | 16.4 | 25 | 15.1 | |
MI 1 – 30 days | 492 | 11.2 | 30 | 18.1 | |
MI 31 – 90 days | 209 | 4.7 | 8 | 4.8 | |
MI 6 – 24 h | 18 | 0.4 | 2 | 1.2 | |
No previous MI | 2,962 | 67.2 | 100 | 60.2 | |
Hypertension | <0.01 | ||||
No hypertension | 1,084 | 24.6 | 29 | 17.5 | |
Treated or BP >140/90 on >1 occasion | |||||
prior to admission | 3,102 | 70.4 | 121 | 72.9 | |
Unknown | 220 | 5 | 16 | 9.6 | |
Smoking | 0.93 | ||||
Current smoker | 626 | 14.2 | 25 | 15.1 | |
Ex-smoker | 2,240 | 50.8 | 85 | 51.2 | |
Never smoked | 1,540 | 35 | 56 | 33.7 | |
Diabetic? | 0.143 | ||||
Not diabetic | 3,547 | 80.5 | 126 | 75.9 | |
Diabetic | 859 | 19.5 | 40 | 24.1 | |
Carotid occlusion | 0.985 | ||||
No | 4,285 | 98.2 | 163 | 98.2 | |
Yes | 78 | 1.8 | 3 | 1.8 | |
Claudication | <0.05 | ||||
No | 3,836 | 87.3 | 134 | 80.7 | |
Yes | 556 | 12.7 | 32 | 19.3 | |
Additive EuroSCORE | 4.9 ± 3.1 | 9.0 ± 3.8 | <0.001 | ||
Logistic EuroSCORE (% predicted mortality) | 5.9 ± 8.3 | 18.9 ± 18.2 | <0.001 | ||
Cardiogenic shock | <0.001 | ||||
No | 4,363 | 99 | 153 | 92.2 | |
Yes | 43 | 1 | 13 | 7.8 | |
Pre-operative IABP | <0.001 | ||||
No | 4,206 | 95.5 | 200 | 84.5 | |
Yes | 200 | 4.5 | 26 | 15.7 | |
Cardiac procedure | <0.001 | ||||
CABG | 2,525 | 57.3 | 51 | 30.7 | |
CABG + other | 26 | 0.6 | 5 | 3 | |
CABG + valve | 540 | 12.3 | 33 | 19.9 | |
CABG + valve + other | 28 | 0.6 | 7 | 4.2 | |
Other | 100 | 2.3 | 23 | 13.9 | |
Valve | 1,055 | 23.9 | 35 | 21.1 | |
Valve + other | 132 | 3.0 | 12 | 7.2 | |
Operative priority | <0.001 | ||||
Elective | 3,288 | 74.6 | 89 | 53.6 | |
Emergency | 132 | 3 | 24 | 14.5 | |
Salvage | 2 | 0 | 3 | 1.8 | |
Urgent | 984 | 22.3 | 50 | 30.1 | |
Bypass time, min | 109 ± 48 | 160.7 ± 92.7 | <0.001 | ||
Cross-clamp time, min | 79.3 ± 89.5 | 97.4 ± 54.8 | <0.05 | ||
Bloods transfused total (red cell concentrate units) | 2.1 ± 38.7 | 4.4 ± 5.8 | 0.45 | ||
Post-operative AKI | <0.001 | ||||
No | 3,906 | 88.7 | 97 | 58.4 | |
Yes | 500 | 11.3 | 69 | 41.6 |
Summary of key pre-operative and peri-operative characteristics of subjects stratified by post-operative survival vs. mortality. p values quoted were calculated using Pearson χ2 tests and unpaired t tests with Bonferroni correction. CABG = Coronary artery bypass grafting; IABP = intra-aortic balloon pump; MI = myocardial infarction.