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. Author manuscript; available in PMC: 2021 Jun 16.
Published in final edited form as: Neuroscience. 2017 Apr 13;368:246–255. doi: 10.1016/j.neuroscience.2017.04.005

Figure 2. Thalamic calcium waves communicate sensory modalities and regulate S1 barrels formation.

Figure 2

(A) Embryonic Ca2+ waves propagate among principal thalamic sensory nuclei and reach the neocortex through thalamocortical axons at E16.5 in mice. (B) Bilateral embryonic enucleation at E14.5 triggers more Ca2+ waves in VPM and LGN, eventually leading to an increment in barrel size and posteromedial barrel subfield (PMBSF) area. (C) Silencing Ca2+ waves in the MGv increases Ca2+ waves frequency in the VPM. This change precedes barrel and PMBSF area enlargement.