Skip to main content
. Author manuscript; available in PMC: 2021 Jun 17.
Published in final edited form as: Diabetes. 2020 Jan 8;69(5):1072–1082. doi: 10.2337/db19-0862

Table 2. GWAS summary statistics in the UK Biobank for the 20 SNPs located in loci not previously reported or in low linkage disequilibrium (r 2<0.1) with lead SNPs previously reported.

Comparisons with publicly available data from the CKDGen consortium and lookups in the EXTEND study can be found in Supplementary Tables 2 and 3, respectively.

Nearest Gene SNP Chr Position (b37) EA/OA EA Freq Beta SE P
MST01 rs35202981 1 155578042 G/A 0.139 0.017 0.003 1.4E-08
EDEM3 rs78444298 1 184672098 G/A 0.980 0.045 0.007 1.4E-09
GPD2 rs111688960 2 157599687 A/G 0.013 0.051 0.009 1.2E-08
FAT1 rs62342738 4 187656129 C/G 0.181 0.015 0.003 5.5E-09
C5orf56 rs11242113 5 131777234 A/G 0.188 0.016 0.003 1.6E-09
KCNK5 rs1544935 6 39124448 G/T 0.216 0.017 0.002 2.2E-11
VEGFA rs3734692 6 43817791 T/A 0.310 0.016 0.002 1.8E-13
AUTS2 rs35692677 7 69902654 G/A 0.813 0.015 0.003 1.1E-08
ZBTB1 rs11990607 8 81363534 A/G 0.835 0.015 0.003 2.5E-08
MLLT10 rs6482189 10 21889138 G/A 0.683 0.013 0.002 1.6E-09
CYP26A1 rs2068888 10 94839642 G/A 0.550 0.012 0.002 1.0E-09
SBF2 rs11042685 11 10262551 C/T 0.493 0.011 0.002 2.1E-08
NUMA1 rs7115200 11 71752160 G/T 0.440 0.012 0.002 1.4E-09
OAF rs12790943 11 120058623 T/C 0.421 0.011 0.002 3.0E-08
NAV3 rs10860332 12 78748014 A/G 0.414 0.011 0.002 4.4E-08
DLEU1/BCMS rs3116613 13 51143055 G/T 0.211 0.014 0.002 3.9E-08
WDR81 rs550628400 17 1639795 G/A 0.006 0.075 0.013 2.1E-08
CYP2A7 rs79600176 19 41392490 T/C 0.978 0.038 0.007 3.6E-08
CCDC97 rs56254331 19 41826020 A/C 0.831 0.017 0.003 7.9E-10
ZBTB46 rs11697610 20 62379531 G/A 0.387 0.012 0.002 1.9E-08

SNP = single nucleotide polymorphism; b37 = build 37; EA/OA = effect allele / other allele; Freq = Frequency; SE = standard error; P = P-value.