Table II. Characterization of the BSA Nanoparticles obtained using three different methods.
Method | Diameter (nm) | PDI | Zeta Potential (mV) | % | Loading efficiency (μg DNA/mg BSA) | |
---|---|---|---|---|---|---|
BSA NP Yield | DNA Encapsulation | |||||
1 | 149 ± 2.51 | 0.13 ± 0.01 | −14.1 ±0.75 | 81.10 ± 2.35 | 63 ± 2.12 | 11.66 ± 1.87 |
2 | 147 ± 3.03 | 0.07 ± 0.005 | −13.8 ± 0.54 | 75.80 ± 1.86 | 61 ± 3.53 | 12.07 ± 2.65 |
3 | 132 ± 1.9 | 0.05±0.01 | −20.5 ± 1.2 | 95.13 ± 1.65 | 85 ± 1.27 | 13.40 ± 1.33 |