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. Author manuscript; available in PMC: 2021 Nov 30.
Published in final edited form as: Nat Metab. 2021 May 31;3(6):829–842. doi: 10.1038/s42255-021-00395-7

Extended Data Fig. 3. The liver-clock does not affect clock-rhythmicity in other peripheral tissues.

Extended Data Fig. 3

Quantitative PCR results of clock gene expression of liver-clock mutant mice (BLKO), fed either ad libitum (AL, upper panels) or exclusively during the light-phase (DF, lower panels) for 30 days. Samples were collected at 2 h intervals for 24 h (n=2 biologically independent mice per time point). Presented are representative clock genes from the (a) Liver, (b) White Adipose Tissue (WAT), (c) Lung, (d) Quadriceps muscle, (e) Kidney, and (f) Heart. Dots mark individual measurements in each Zeitgeber Time (ZT). Significant rhythms according to JTK_CYCLE are denoted by cosine fit curve according to the captions, with a vertical line representing the phase; dashed curves represent non-significant (ns) rhythms.