Table 1. Published evidence comparing CMR and PET quantitative perfusion imaging: principal methodological characteristics and results.
Year | Author | Reference | n | Type of participants | CMR perfusion protocol | Stressor | Quantitative analysis CRM method | PET radiotracer | Quantitative angiography (% significant stenosis) | Sensitivity* | Specificity* | Agreement between CMR/ PET-derived indices** |
---|---|---|---|---|---|---|---|---|---|---|---|---|
2001 | Schwitter J | 34 | 66 | Healthy volunteers 18 and CAD 48 | 1.5 T mulislice hybrid echo-planar pulse sequence | Dipyridamole | Semi-quantitative | 13NH3 | Performed (>50%) | 91% | 94% | MBF: r. not stated MPR: r. 0.76x |
2002 | Ibrahim T | 35 | 44 | Healthy volunteers 19 and CAD 25 | 1.5 T, Multislice ultra-fast hybrid sequence | Adenosine | Semi-quantitative | 13NH3 | Performed (>50%) | 86% | 84% | MBF: r. not stated MPR: r. 0.70 |
2006 | Pãrkkã JP | 36 | 18 | Healthy volunteers | 1.5 T, saturation recovery turboFLASH sequence | Dipyridamole | Quantitative | (15O)H2O | Not performed | - | - | MBF: r. 0.70 MPR: r. 0.46 |
2008 | Fritz-Hansen | 38 | 10 | Healthy volunteers | 1.5 T, ECG-triggered saturation recovery turboFLASH sequence | Dipyridamole | Quantitative | 13NH3 | Not performed | - | - | MBF: r. 0.79 MPR.: r. Not stated |
2008 | Pack N | 72 | 5 | Healthy volunteers | 3 T, saturation recovery turboFLASH sequence | Adenosine | Quantitative | 13NH3 | Not performed | - | - | MBF: r. 0.85 MPR.: r: Not stated |
2012 | Morton G | 37 | 38 | CAD | 1.5 T, k-t balanced turbogradient echo sequence | Adenosine | Quantitative | 13NH3 | Performed (>70%) | - | - | MBF: r. 0.32 MPR: r. 0.79 |
n, Number of patients; CAD, coronary artery disease; CMR., cardiac magnetic resonance; PET, positron emission tomography; MBF, myocardial blood flow; MPR, myocardial perfusion reserve
Detection of CAD by CMR-derived MPR. against PET-derived MPR.
Correlation coefficient