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. Author manuscript; available in PMC: 2021 Jul 12.

Published in final edited form as: Nat Chem Biol. 2017 Jun 12;13(8):882–887. doi: 10.1038/nchembio.2404

Genetic interaction between OGT/sxc^H537A and Gug⁰³⁹²⁸ or mop^T482 alleles was assessed in the adult wing. In the Cr control (a), OGT/sxc^H537A (b) homozygotes or Gug⁰³⁹²⁸ or mop^T482 heterozygotes have a complete L5 longitudinal wing vein that reaches the wing margin. In OGT/sxc^H537A/OGT/sxc^H537A;Gug⁰³⁹²⁸/+ (c) or OGT/sxc^H537A/OGT/sxc^H537A;mop^T482/+ (d) flies, 14% and 8% of the flies, respectively, have a shorter L5 wing vein. Fewer of the double homozygotes, OGT/sxc^H537A/+;Gug⁰³⁹²⁸/+ or OGT/sxc^H537A/+;mop^T482/+ display this phenotype as demonstrated by the quantification in (e). Arrows in (c) and (d) point to the short L5 wing vein phenotype.

Genetic interaction between OGT/sxc^H537A and Gug⁰³⁹²⁸ or mop^T482 alleles was assessed in the adult wing. In the Cr control (a), OGT/sxc^H537A (b) homozygotes or Gug⁰³⁹²⁸ or mop^T482 heterozygotes have a complete L5 longitudinal wing vein that reaches the wing margin. In OGT/sxc^H537A/OGT/sxc^H537A;Gug⁰³⁹²⁸/+ (c) or OGT/sxc^H537A/OGT/sxc^H537A;mop^T482/+ (d) flies, 14% and 8% of the flies, respectively, have a shorter L5 wing vein. Fewer of the double homozygotes, OGT/sxc^H537A/+;Gug⁰³⁹²⁸/+ or OGT/sxc^H537A/+;mop^T482/+ display this phenotype as demonstrated by the quantification in (e). Arrows in (c) and (d) point to the short L5 wing vein phenotype.