Table 1. Summary description of haematological parameters and measurement/calculation methods by UK Biobank.
| Haematological parameter | Description | Measurement/calculation |
|---|---|---|
| Red blood cell | ||
| Red blood cell count (1012 cells/L) | Number of red blood cells in the sample | Measured |
| Red blood cell distribution width (%) | Spread of red blood cell population | Deriveda |
| Haematocrit (%) | Volume occupied by red blood cells in the blood | (MCV x RBC)/10 |
| Haemoglobin concentration (g/dL) | Total haemoglobin concentration in sample | Measured |
| Mean corpuscular volume (pg) | Average volume of red blood cells | Deriveda |
| Mean corpuscular haemoglobin (g/dL) | Mass of haemoglobin in the average red blood cell | (HGB / RBC) x 10 |
| Mean corpuscular haemoglobin concentration (g/dL) | Average mass of haemoglobin per the relative volume of red blood cells in the whole blood sample | (HGB / HCT) x 100 |
| Reticulocyte count (1012 cells/L) | Number of reticulocytes in the red blood cell sample | % Reticulocyte x RBC |
| Platelet | ||
| Platelet count (109 cells/L) | Number of platelets in the sample | Measured |
| Platelet distribution width (%) | Variation in platelet volume | Deriveda |
| Mean platelet volume (fL) | Average volume of individual platelets in the sample | Deriveda |
| White blood cell | ||
| White blood cell count (109 cells/L) | Number of white blood cells in the sample | Measured |
| Neutrophil count (109 cells/L) | Number of neutrophils in the white blood cell sample | (% Proportion of neutrophils/100) x WBC |
| Eosinophil count (109 cells/L) | Number of eosinophils in the white blood cell sample | (% Proportion of eosinophils/100) x WBC |
| Basophil count (109 cells/L) | Number of basophils in the white blood cell sample | (% Proportion of basophils/100) x WBC |
| Monocyte count (109 cells/L) | Number of monocytes in the white blood cell sample | (% Proportion of monocytes/100) x WBC |
| Lymphocyte count (109 cells/L) | Number of lymphocytes in the white blood cell sample | (% Proportion of lymphocytes/100) x WBC |
Measurement/calculation methods were obtained from: http://biobank.ctsu.ox.ac.uk/crystal/docs/haematology.pdf.
a
Derived values were calculated within the instrument using multiple scatterplots and histograms for each sample.
Abbreviations: HCT=haematocrit; HGB=haemoglobin concentration; MCH=mean corpuscular haemoglobin; MCHC=mean corpuscular haemoglobin concentration; MCV=mean corpuscular volume; MPV=mean platelet volume; PDW=platelet distribution width; PLT=platelet count; RBC=red blood cell count; RCDW=red blood cell distribution width; RET=reticulocyte count; WBC=white blood cell count.