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. Author manuscript; available in PMC: 2021 Jul 19.
Published in final edited form as: Clin Cancer Res. 2019 Sep 24;25(24):7436–7447. doi: 10.1158/1078-0432.CCR-19-0360

Figure 2.

Figure 2

Photoacoustic images displayed as maximum intensity projections (MIPs) showing the longitudinal response of a SW1222 tumor (mouse m4sw) to 40mg/kg IV dose of OXi4503 over 16 days. The horizontal x-y maximum intensity projections (MIP) are for z = 1 - 6 mm. The tumour region in the pre-treatment image is indicated by yellow arrows. After treatment a region in the tumor core characterised by a lack of PAI contrast can be seen. This void diminishes over the 16 time course, with PA signal returning to areas of the tumor core.