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. Author manuscript; available in PMC: 2021 Jul 20.
Published in final edited form as: Cancer Res. 2019 Jul 16;79(18):4627–4637. doi: 10.1158/0008-5472.CAN-18-3594

Table 1. 2’O-MeRNA oligonucleotide sequences. The template region of hTR is shown in bold and mismatched bases are underlined. For reference, the sequence of GRN163L (Imetelstat) is also shown.

Oligonucleotide Sequence 5’-3’ Modification 5’-end
hTR template (3’-5’) GUCAAUCCCAAUCUGUU - -

GRN163L TAGGGTTAGACAA - -
Match CAGUUAGGGUUAG 2’OMeRNA Amine (AmC6)
Mismatch 1 CAGUUACGCUUAG 2’OMeRNA Amine (AmC6)
Mismatch 2 CAGAUACGCUUAG 2’OMeRNA Amine (AmC6)
Scramble GCAGUGUGAUGAU 2’OMeRNA Amine (AmC6)