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. Author manuscript; available in PMC: 2021 Jul 20.
Published in final edited form as: FASEB J. 2020 Jun 5;34(7):9664–9677. doi: 10.1096/fj.202000697R

Figure 5. Reactive oxygen species and senescence pathways.

Figure 5

Data are mean ± SEM. A, Protein carbonylation as compared to control samples. B, OxyBlot bands for quantification of protein carbonylation. Sample 6 was within the 2SD margin, and therefore, not excluded from the control group. C, Illustration of ROS mediated cell senescence pathway. D, mRNA expression of antioxidants Catalase, Super Oxide Dismutase 1 (SOD1), Super Oxide Dismutase 2 (SOD2), and Glutathione peroxidase (GPx), E, mRNA expression of MKK3 (also known as MAPKK3), F, mRNA expression of p38-MAPK, G, mRNA expression of p16. Significant difference *P < .05 vs control. Student’s t test for unpaired data