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. Author manuscript; available in PMC: 2022 Jan 21.
Published in final edited form as: Bioconjug Chem. 2020 Aug 27;32(7):1276–1289. doi: 10.1021/acs.bioconjchem.0c00401

Figure 5. Binding of each radiotracer to an array of calcium salts in saline and at room temperature.

Figure 5

(A) [68Ga]Ga-THP-Pam binding, blocking with pamidronate. (B) [68Ga]Ga-BPAMD binding, blocking with alendronate. (C) [68Ga]Ga-NO2APBP binding, blocking with pamidronate. (D) [18F]NaF binding, blocking with sodium fluoride. (E) Comparison of the mean binding to HAp of 68Ga-BPs and [18F]NaF. (F) Comparison of the mean binding to non-HAp calcium salts of 68Ga-BPs and [18F]NaF. HAp = hydroxyapatite; CC = calcium carbonate; CP = calcium phosphate dibasic; CPy = calcium pyrophosphate; β-TCP = β-tricalcium phosphate; CO = calcium oxalate monohydrate.