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. Author manuscript; available in PMC: 2021 Jul 22.
Published in final edited form as: Bioconjug Chem. 2020 Nov 26;32(7):1242–1254. doi: 10.1021/acs.bioconjchem.0c00561

Figure 6. Effect of cysteine and methionine.

Figure 6

A. Radiochemical yield for the seven Cys-containing sequences appearing among the ten best labeling sequences, compared to otherwise identical partner “mutants” in which Cys was deleted or substituted. In all but one pair, the Cys-containing sequence showed higher labeling efficiency (*** p < 0.001; ** p < 0.05). B. Comparison of labeling efficiency of identical peptide sequences in which a Cys residue is replaced by a Met amino acid. For four of the pairs, the corresponding sequence with neither Cys or Met is also included.