Figure 2.

Maps of the voxel-wise diffusion-defined volume fractions obtained with the multi-shell multi-tissue algorithm. This figure shows the maps of voxel-wise volume fractions of the tissues defined based on their diffusion properties. As can be seen in panel (a), the multi-shell multi-tissue algorithm successfully differentiated the different types of brain tissue: normal-appearing WM (i.e. anisotropic tissue), CSF (i.e. isotropic tissue 1) and GM (isotropic tissue 2). WM lesions (panel (b)) were mainly captured by the isotropic tissue 2 and partly by the anisotropic tissue.

WM: white matter.