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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Nat Struct Mol Biol. 2021 Jun 10;28(6):512–520. doi: 10.1038/s41594-021-00605-6

Extended Data Fig. 5. WT ELOVL7 activity.

Extended Data Fig. 5

a,b Activity of residual WT enzyme on incubation with stearoyl-CoA (C18:0) and malonyl-CoA. Selected ion recording is shown for a, reaction mixture without added enzyme and b, reaction mixture after 3hr incubation with ELOVL7 enzyme. The ion peak at 1.61 mins corresponds to the expected 3-keto-eicosanoyl (C20)-CoA product of the elongation reaction. This experiment was carried out with two biological repeats with similar results.