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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Nat Struct Mol Biol. 2021 Jun 10;28(6):512–520. doi: 10.1038/s41594-021-00605-6

Fig. 7. Model for malonyl-CoA binding at the decarboxylation site.

Fig. 7

a, Putative structural model for malonyl-CoA (MLC) binding within the conserved decarboxylation side pocket off the main tunnel. b, Conserved sidechains recognise malonyl carboxylate (viewed looking from H150). c, Composite structural model of second condensation reaction step with bound acy-limidazole intermediate and malonyl-CoA.