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Illustration of the degree of diffusion restriction in different directions measured using fractional anisotropy (FA). In voxels consisting of coherently aligned myocytes, the FA is expected to be high whereas it is expected be low in voxels with disorganised myocyte orientation such as hypertrophic cardiomyopathy. Reproduced with permission from Tarkin et al.42 ECV, extracellular volume; HCM, hypertrophic cardiomyopathy.
