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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: Neuroimage. 2018 Nov 19;186:464–475. doi: 10.1016/j.neuroimage.2018.11.023

Fig. 1.

Fig. 1

Workflow and signal equation for multi-contrast PD estimation. The signal (S) of FLASH multi-echo PDw, T1w, and MTw images was combined and corrected for R2* relaxation. The resulting PDw and T1w images were corrected for R1 and inhomogeneity in the transmit magnetic field (B1+) by computing voxel-wise the steady state (ST) term. MTw images were corrected for STMT computed using the magnetisation saturation (MT) term. This led to three maps representing the signal amplitude common to the three FLASH datasets. The mean of the three images was corrected for the receiver profile (RP) using N4ITK, and scaled using the median signal of the external calibration object (C).