Extended Data Fig. 6. E-cadherin removal does not affect the contractile behaviour of single cells.

a) Mean traction force for both MDCK WT (n=31) and MDCK Ecadherin KO cells (n=27). b) Average yy- and xy-components of strain rate map around comet (+1/2) defect obtained from experiments (left and middle respectively) and corresponding average velocity flow field (right) (n = 1428 defects from 2 independent experiments) for MDCK E-cadherin KO cells plated on PDMS substrates of stiffness 15kPa from which stress maps were obtained in Figure 3b’.