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. Author manuscript; available in PMC: 2021 Aug 4.
Published in final edited form as: Clin Cancer Res. 2021 May 20;27(15):4311–4324. doi: 10.1158/1078-0432.CCR-21-0136

Figure 2. Sex-based differences in abundance of specific CD8+ (panel A) and CD4+ (Panel B) T-cell subpopulations.

Figure 2

Figures in panel A and B, show respectively the branched trajectory of CD8+ T and CD4+ T cells state transition in a two-dimensional state-space as described in Guo et al. Each dot corresponds to a T-cell subpopulation, colored according to its cluster label. Arrows show the increasing directions of certain T cell properties.

Tables in panel A and B report sex-based difference in abundance of each specific CD8+ T and CD4+ cell subpopulation: NES >0 indicates enrichment in tumors of women, NES<0 in tumors of men