Table 1. Clinical characteristics of patients at baseline.
| Characteristic | Atovaquone cohort n=23 | No atovaquone cohort n=23 |
|---|---|---|
| Age (yr) | 69.7 (58.5, 74.1) | 68.6 (62.4, 71.4) |
| Sex | ||
| Male | 11 (47.8) | 17 (73.9) |
| Female | 12 (52.2) | 6 (26.1) |
| Ethnicity | ||
| White | 23 (100) | 23 (100) |
| Smoking Status | ||
| Never smoker | 0 (0.0) | 2 (8.7) |
| Ex-smoker | 22 (95.7) | 21 (91.3) |
| Current smoker | 1 (4.4) | 0 (0.0) |
| ECOG performance status | ||
| 0 | 16 (69.6) | 16 (69.6) |
| 1 | 7 (30.4) | 7 (30.4) |
| Histologya | ||
| Adenocarcinoma | 15 (65.2) | 11 (47.8) |
| Squamous cell carcinoma | 7 (30.4) | 8 (34.8) |
| Adenosquamous carcinoma | 1 (4.4) | 0 (0.0) |
| Large cell | 0 (0.0) | 1 (4.4) |
| Giant cell carcinoma | 0 (0.0) | 1 (4.4) |
| Pleomorphic carcinoma | 0 (0.0) | 1 (4.4) |
| Not otherwise specified | 0 (0.0) | 1 (4.4) |
| TNM stagea | ||
| T1b | 0 (0.0) | 1 (4.4) |
| T1c | 2 (8.7) | 1 (4.4) |
| T2vis | 1 (4.4) | 2 (8.7) |
| T2a | 3 (13.0) | 4 (17.4) |
| T2b | 5 (21.7) | 3 (13.0) |
| T3 | 7 (30.4) | 5 (21.7) |
| T4 | 5 (21.7) | 7 (30.5) |
| N0 | 13 (56.5) | 12 (52.2) |
| N1 | 7 (30.4) | 8 (34.8) |
| N2 | 3 (13.0) | 3 (13.0) |
| M0 | 23 (100.0) | 22 (95.7) |
| M1b | 0 (0.0) | 1 (4.4) |
| Tumor maximum diameter (mm) | 45 (33, 60) | 44 (29, 60) |
| Hemoglobin (g/dL) | 13.2 (12.0, 14.3) | 13.9 (12.9, 14.7) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; TNM, tumor, node and metastasis.
Data shown as patient number with percentage or mean with interquartile range.
a
Histology and staging are following resection, unless this was not performed, in which case diagnostic histology and imaging were used, respectively.