Table 3.

Reaction parameters for the copper-catalyzed azide-alkyne cycloaddition reaction of P2HEB-azide and PPDL-alkyne using Cu^I(OAc) as a catalyst and TBD as a base.^a

PPDL-alkyne			P2HEB-azide			CuI(OAc)	PPDL-triazole-P2HEB
Mn b / g mol-1	PDIb	n / mmol	Mn b / g mol-1	PDIb	n / mmol	nc / mmol	Mn b / g mol-1	PDIb	mol%d PPDL	mol%d P2HEB	mass%e PPDL	mass%e P2HEB
6,100	2.45	0.0153	750	1.67	0.0459	0.0153	7,900	1.74	79	21	85	15
21,000	1.72	0.0238	15,000	1.24	0.0714	0.0238	32,000	1.43	66	34	74	26
22,000	2.16	0.0110	24,000	1.23	0.0330	0.0110	48,000	1.47	57	43	66	34
30,000	1.62	0.0200	19,000	1.33	0.0600	0.0200	44,000	1.41	52	48	61	39
6,100	2.45	0.0125	24,000	1.23	0.0041	0.0041	30,000	1.23	21	79	28	72

^aReactions were performed for two days at ambient temperature in chloroform (1-2 mL).

^bNumber-average molecular mass and polydispersity index were determined by GPC in chloroform using PMMA standards.

^cThe same molar amount was used for TBD.

^dMolar ratios were determined by ¹H NMR spectroscopy.

^eCalculated using the molar percentage and molecular mass of the repeat units, with M(PDL) = 240.38 g mol^-1 and M(2,3-DHB) = 164.16 g mol^-1.