Table 3.
Distributions of all patients, stratified according to gender and arm to which they were assigned at randomization (top).
| Characteristic | Minimum | 25% | 50% | 75% | Maximum | |
|---|---|---|---|---|---|---|
| Age (years) | ||||||
| Male | ||||||
| Control | N = 27/27 | 55.4 | 62.4 | 68.5 | 74.2 | 86.5 |
| Metastasectomy | N = 31/31 | 35.3 | 58.5 | 66.4 | 72.1 | 82.8 |
| Female | ||||||
| Control | N = 20/20 | 48.2 | 54.3 | 61.3 | 74.3 | 83.2 |
| Metastasectomy† | N = 14/15 | 50.8 | 64.4 | 71.6 | 64.4 | 76.5 |
| CRC resection interval (months) | ||||||
| Control‡ | N = 46/47 | 2.0 | 17.2 | 27.4 | 35.0 | 130.5 |
| Metastasectomy§ | N = 45/46 | 1.0 | 13.8 | 23.1 | 36.8 | 106.5 |
| Number of metastases | ||||||
| Control¶ | N = 46/47 | 1 | 1 | 2 | 3 | 8 |
| Metastasectomy | N = 46/46 | 1 | 1 | 2 | 3 | 6 |
Values are given as minimum, maximum and quantiles. The quantile distribution of the number of metastases is as follows: for 1, 2, 3, 4 and 5 metastases the exact numbers for control patients were 16, 16, 7, 3 and 3, and for metastasectomy patients they were 16, 17, 8, 2 and 1, with one patient in each arm having more than 5 metastases – 8 and 6, respectively.
We know from minimization data that the age category of the missing patient was 61+ years.
From minimization data, the missing colorectal cancer (CRC) resection interval [i.e., the time elapsed between the primary CRC resection and the metastasectomy operation] was 1–3 years.
The missing CRC resection interval was <1 year.
From minimization data, the metastasis count was >5.