. Author manuscript; available in PMC: 2021 Aug 27.

Published in final edited form as: Birth Defects Res. 2021 Mar 23;113(12):968–980. doi: 10.1002/bdr2.1893

Table 1. Prevalence of NTD-affected pregnancies per 10,000 births (95% CI), by NTD type and whether the NTD was isolated or non-isolated¹. From combined EMSYCAR, NorCAS, SWCAR, CAROBB and CARIS data.

NTD type	Anencephaly (n = 673)	Encephalocele (n = 185)	Spina bifida (n = 784)	Total NTDs (n = 1642)
Isolated (n = 1248)	4.14 (3.81-4.50)	0.79 (0.65-0.96)	4.30 (3.95-4.66)	9.23 (8.73-9.76)
Non-isolated (n = 394)	0.84 (0.69-1.01)	0.57 (0.46-0.72)	1.50 (1.30-1.72)	2.91 (2.63-3.22)
All NTDs	4.98 (4.61-5.37)	1.37 (1.18-1.58)	5.80 (5.40-6.22)	12.14 (11.56-12.75)

Determined using the multiple malformation group variable.

Table 1. Prevalence of NTD-affected pregnancies per 10,000 births (95% CI), by NTD type and whether the NTD was isolated or non-isolated1. From combined EMSYCAR, NorCAS, SWCAR, CAROBB and CARIS data.