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. Author manuscript; available in PMC: 2021 Sep 21.
Published in final edited form as: J Mol Biol. 2016 Jan 11;428(10 Pt A):2011–24. doi: 10.1016/j.jmb.2016.01.002

Fig. 4. An experiment to demonstrate how NTRs in solution can rapidly penetrate FG-domain hydrogels.

Fig. 4

(a) The interface between an FG-domain hydrogel and a buffer solution. Once a fluorescent NTR (importin-β) was added to the buffer solution outside the gel, the NTR rapidly enriched in the gel boundary. (b) Intensity profiles corresponding to the images in (a), from which it is apparent that a depletion zone exists in at the buffer-gel interface. Adapted from Ref. [71] with permission from Elsevier.