Figure 3.
Schematic embodiment of the in silico multiscale CFPD simulation strategy, whereby different compartments of the lungs (i.e., extra-thoracic, conducting trachea-bronchial, conducting mid/small bronchi, acinus) are independently modeled, but simulated in combination, with various degrees of computational efforts invested in each depending on the required outcomes sought (e.g., regional aerosol deposition fraction, etc.).