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. Author manuscript; available in PMC: 2021 Oct 18.
Published in final edited form as: Gastroenterology. 2020 Dec 31;160(5):1784–1798.e0. doi: 10.1053/j.gastro.2020.12.058

Figure 2. Differences in species composition in PSC compared to healthy controls.

Figure 2

(A) Species that were differently abundant and (B) species with different prevalence in PSC and healthy controls. Species are colored by phyla affiliation. (C) Bacterial abundance co-correlation network in healthy controls and (D) PSC patients. In A&B the triangle/bar in the forest plot indicate log(OR)/SE. Red and blue lines in C&D indicate positive and negative correlations between species, respectively. Node-size reflects the square-root transformed median relative abundances in each phenotype, and encircled nodes mark articulations points. Only correlations with r>0.4 are shown, and increasing correlation coefficient are reflected by increasing line thickness. PSC, primary sclerosing cholangitis; HC, healthy controls. *Q fdr<.05, ** Q fdr<.005, *** Q fdr<.0005.